| 存贮条件 | 储存温度2-8℃ |
|---|---|
| 熔点 | 181°C-183°C |
| 密度 | 否 |
| 荧光 | 否 |
| IC50 | 否 |
| pK Values | 否 |
| 别名 | 长春瑞宾双酒石酸盐;3‘,4‘-Didehydro-4‘-deoxy-C‘-norvincaleukoblastine [R-?(R*,R*)?-?2-?3-?dihydroxybutanedioate (1:2)salt], 5‘-Noranhydrovinoblastine tartrate, KW-2307, NVB, Navelbine tartrate |
|---|---|
| 产品介绍 | Vinorelbine ditartrate is a selective mitotic microtubule antagonist that exhibits > 20 fold selectivity over axonal microtubules. This compound has been shown to inhibit the proliferation of multiple human tumor cell lines (IC50 = 1.25 nM in HeLa cells). |
| 生化机理 | Vinorelbine is a potent anti-mitotic, anti-tumor agent. Vinorelbine inhibits microtubule assembly. Low neurotoxicity is related to its higher affinity for mitotic microtubules than for axonal microtubules. |
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